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Celebrity-backed longevity start-up closes US$10m seed round

John Legend, Chrissy Teigen, Pedro Pascal and Zac Efron are among the celebrities who have individually invested in the company

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A US biotech start-up, backed by John Legend, Chrissy Teigen and Zac Efron, has secured US$10m in funding to “change” the way people age.

Tally Health, founded by Dr David Sinclair and serial entrepreneur Whitney Casey, aims to improve healthspan and extend longevity at the cellular level using epigenetic age tests, personalised lifestyle recommendations and longevity supplements.

The new capital, the New York-based company says, will support the research and development of new products, additional features, and technology integrations to allow users to integrate the feedback of their epigenetic age test into their daily lifestyle digitally.

“This financing underscores the significant and growing consumer interest in healthspan and longevity,” said Melanie Goldey, CEO of Tally Health.

“I am pleased to see our 270,000+ pre-launch waitlist converting as we attract new members, investors, and celebrities who believe in our mission to increase healthspan, drive impactful lifestyle changes, and extend human healthspan and longevity.”

Consumer interest in the longevity space has exploded in recent years, with the global longevity economy projected to reach an astounding US$27t in 2026 and the agetech segment reaching US$2.7t by 2025, according to Longevity Technology.

Kirsten Green, founding partner at Forerunner Ventures, which led the funding round, said: “Longevity presents a remarkable, untapped opportunity, particularly in the context of its fundamental, universal importance — everyone ages, and increasingly savvy, health-conscious generations are highly motivated to have more agency over the process and ultimately live a more fulfilling life.

“The Tally Health team is in a category-defining position to open up access to scientific breakthroughs that not just slow aging, but can even help reverse it.”

Celebrities including John Legend, Chrissy TeigenPedro Pascal, Shonda Rhimes, Kevin HartRich RollWhitney Cummings, and Zac Efron have individually invested in the longevity start-up.

Whitney Casey, co-founder of Tally Health and partner at L Catterton, said: “We founded Tally Health based on pure demand for more science-backed longevity innovations for consumers.

“We are able to scale learnings from breakthrough epigenetic research with our own proprietary technologies to bring the science in-home for our members.

“There is a growing global consumer interest in evaluating health through the lens of longevity, and Tally Health’s continued growth will propel the agetech sector forward.”

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Disadvantaged neighbourhoods linked to faster heart health decline in midlife women, research shows

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Women in disadvantaged areas may face poorer heart health and faster decline as they approach menopause, new research suggests.

Researchers followed 1,200 women in eastern Massachusetts for more than 20 years, from pregnancy into midlife.

The study measured heart health at five points using a score based on eight health and lifestyle factors, including blood pressure, cholesterol, sleep, diet and physical activity.

Women living in the most socially vulnerable neighbourhoods scored about six to 10 points lower on heart health across more than two decades of follow-up than those in the least disadvantaged neighbourhoods.

The differences were already clear three years after enrolment and continued into midlife.

Researchers also found that women in these neighbourhoods had faster declines before menopause, the stage when periods stop and cardiovascular risk can rise. Cardiovascular health means the health of the heart and blood vessels.

Socioeconomic factors also appeared to shape outcomes. Women with lower income, less education, or who identified as non-Hispanic Black had lower heart health scores throughout the study.

The findings highlight how long-term exposure to social and environmental conditions may affect cardiovascular risk over time.

Even modest differences in heart health scores may matter, as previous research has linked small decreases in these scores with higher risks of cardiovascular disease and death.

Senior author Izzuddin Aris, associate professor at Harvard Medical School and the Harvard Pilgrim Health Care Institute, said: “Our study shows that heart health in midlife is shaped by more than personal choices. Income, education, and neighbourhood conditions may all play a role.”

Neighbourhood conditions continued to affect heart health even after researchers took income and education into account.

Women who lived for years in highly vulnerable neighbourhoods had persistently lower scores and poorer cardiovascular health trajectories.

Aris added: “The years before and around menopause may be an important time to support women’s heart health.

“This is especially true for women living in under-resourced neighbourhoods.”

The findings suggest prevention efforts could include better access to healthy food, safe places to be active and quality healthcare, particularly for women seeking to protect their heart health over time.

The study used data from Project Viva, a long-term research study that has followed women since pregnancy in the early 2000s through midlife.

Researchers collected repeated health data over more than two decades, allowing them to track long-term patterns in heart health.

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Entrepreneur

What “women’s healthmaxxing” means for patient trust and the femtech industry

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Women’s health has become one of the most searched and shared topics online, from cycle syncing and cortisol management to menopause hacks, supplements, hormone testing and clinician-creator content.

That surge in attention, sometimes dubbed “healthmaxxing,” is changing how women find, evaluate and act on health information, and it is starting to reshape the relationship between patients, clinicians and the companies building products for this market.

For providers, the shift means patients are arriving better informed but also more exposed to unverified claims, putting pressure on clinicians to engage with online narratives rather than dismiss them.

For femtech and pharma companies, it opens a route to reach and educate consumers at scale, but also raises the stakes on credibility: products and messaging that ride the trend without clinical grounding risk eroding the trust the industry has spent years building.

Investors are watching the same dynamic from a different angle.

Attention-driven demand can be a signal of where the next wave of femtech growth will come from, but distinguishing genuine clinical need from viral momentum is increasingly part of due diligence.

The net effect is a widening gap between companies that treat cultural attention as a distribution channel for credible, evidence-based care, and those that risk being swept up in trends with little clinical substance behind them.

How that gap plays out will shape patient trust, clinical relationships and commercial opportunity across the women’s health industry for years to come.

These themes will be explored in more depth in an upcoming webinar, “Women’s Healthmaxxing: The Opportunity & Risks of Cultural Attention for the Women’s Health Industry,” hosted by the Women’s Health Innovation Summit (WHIS), featuring Ellen Wilcox (Listen Ventures), Jessica Bell van der Wal (Frame Fertility), Dr. Tosin Sotubo-Ajayi (NHS, BBC and more) and Nora Lansen (Elektra Health).

Register free for the webinar on 23 July 2026 at https://events.virtualpro.com/womens-health-series-webinar-july-2026/registration

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Rising number of young midwives quitting NHS due to burnout

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More young midwives are leaving the NHS before 35 as burnout adds pressure to stretched maternity services, new research has revealed.

The trend has raised concerns about the quality and safety of care for mothers and babies in understaffed maternity units.

During 2025-26, 1,669 midwives aged 34 or under left the health service in England, representing 57 per cent of the 2,949 midwives of all ages who resigned.

The pressures of maternity care, including increasingly complex childbirth and the risks involved, are thought to be among the factors behind the trend.

Hannah Leonard, deputy chief midwife at the Royal College of Midwives, said the exodus of midwives under 35 was “deeply worrying” and showed that too many were ending up “burnt-out within a few years of qualifying because every shift means too few colleagues, missed breaks and unpaid hours”.

She added: “Losing these midwives, and students, even before they qualify, is a terrible waste of talent.”

The figures, revealed in parliamentary questions tabled by the Liberal Democrats, show that 205 of last year’s younger leavers were under 25, while 655 were aged 25 to 29 and 809 were aged 30 to 34.

The number of midwives under 35 leaving the NHS has risen sharply in recent years. The 2025-26 figure was 59 per cent higher than the 1,051 who left in 2014-15, according to NHS figures.

Burnout means long-term physical and emotional exhaustion, often linked to sustained pressure at work.

Separate figures obtained by the Liberal Democrats suggest almost one in four midwifery students are leaving before completing their three-year degree.

In 2021, 3,565 students started a midwifery degree, but 2,725 graduated in 2024, meaning 840, or 24 per cent, did not complete the course.

Midwifery students spend much of their second and third years learning on the job in maternity units.

The loss of staff and students underlines what the Royal College of Midwives has described as a “staffing emergency” in maternity care across the UK.

A recent survey by the Royal College of Midwives found that three-quarters of midwives had considered leaving the profession over the last year, mainly because of concerns over staffing levels and patient safety.

Both recent large-scale reviews of maternity care in England, led by Donna Ockenden and Valerie Amos, identified staffing shortages as a key problem affecting patient safety.

Helen Morgan, the Liberal Democrat health spokesperson, said: “These statistics reveal an alarming crisis in maternity, with far too many midwives burning out early in their career and in their training. Patients are paying the price, and mothers are left with no alternative but to give birth on understaffed and unsafe wards.

“Rather than throw money at yet more new recruits who quit under intolerable pressure, the government needs a new approach. Through guaranteeing protected, year-round training and professional development we can help midwives cope with rising complexity and risk.”

About 10 per cent of all midwives leave the NHS each year.

However, the figures show higher leaving rates among younger midwives, with one in seven, or 14.6 per cent, of those aged 25 to 29 and one in six, or 16.6 per cent, of those aged 30 to 34 leaving during 2025-26.

A Department of Health and Social Care spokesperson said: “Under this government we have a record number of midwives in the workforce and we value the vital service they provide in maternity and neonatal units across the country.

“To make the NHS the best employer it can be, we have introduced new NHS staff standards to improve health and wellbeing support, promote flexible working, as well as crucial measures to tackle violence, sexual harassment or abuse and racism.

“Alongside consecutive above-inflation pay rises, we’ve bolstered the midwifery workforce through our graduate guarantee and recently opened up 1,000 more midwifery roles backed by £10m to help prevent student midwives leaving the profession.”

Department of Health and Social Care figures show a record 25,500 full-time-equivalent midwives are working in the NHS, 2,000 more than when the Labour government took office in July 2024.

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