Fertility
How AI could revolutionise implantation prediction

Fairtility’s Cristina Hickman tells us how AI could change the fertility world and what it would mean for thousands of aspiring parents.
In vitro fertilisation (IVF) is the most effective form of assisted reproductive technology. Due to the complexity of the procedure, however, prediction of embryonic implantation prior to IVF is key in decision-making.
The Israeli software company Fairtility aims to maximise IVF outcomes by using AI and computer vision algorithms to analyse morphological and morphokinetic features and provide early, data-driven embryo quality.
“It’s essentially an assistant that supports embryologists and gives them superpowers,” says Dr Cristina Hickman, researcher and embryologist. “Using computer science that highlights the things that we may have missed [in the embryo selection process] is a completely different way of practising biology compared to how we did it before.”
The AI-based system could, in fact, standardise the practice, she explains. “We want patients to get access to the best possible treatment all the time. Very often different embryologists look at different pieces of information. So, the tools that we use will have an impact both in terms of improving our ability to pick the correct embryo, but also in terms of enhancing consistency in practice.
“We already have a number of studies that we’ve done with several different clinics to show how embryologists assess the embryos and how the AI systems assess the embryos,” Hickman continues. “We’re not disagreeing with each other. We just make the whole process faster and consistent, so that over time, we can get to the point where we can bring more cycles per embryologist and make treatments more affordable.”
The other benefit of the algorithm would be a better understanding of the IVF success rates. According to the Society for Assisted Reproductive Technology (SART), patients have rated the stress of undergoing IVF as more stressful than or almost as stressful as any other major life event, such as the death of a family member, separation or divorce. “Analysing the embryo would allow us to see any anomalies and see if it has a very low chance of becoming a healthy baby,” says Dr Hickman.
“Within a touch of a button, the embryologist has the ability to share information with the patients directly from the system. For example, they can see images, videos and even summary reports saying how many embryos are fertilised. Therefore, all patients can have this experience of transparency and they can see what the embryologist sees.
“They can also understand the risk of getting a negative result and they don’t have to go through that emotional roller coaster,” the researcher adds. “This means that the patients would be in a better emotional position to go back and do another cycle because they understood this journey a little bit better. Our aim overall is to bring less stress and more stability in this process.”
Dr Hickman argues that the management of expectations of patients is incredibly important in IVF and there is no such thing as a one-size-fits-all approach. “Not everybody has the same chance of pregnancy and this personalisation in the way we deliver information is based on what we know about the embryo.
“Historically, we used to speak to two different patients in exactly the same way,” she says. “But we may have a patient who has a very high chance of pregnancy and one that has a very low chance of pregnancy and therefore, the latter is actually going to suffer more by receiving that super positive feedback.
“The transparency, I think, is crucial to that relationship between the facility professional and the patient. While it might seem harsh to provide the full information upfront, in my experience the patients feels more comforted and they trust us more.”
Hickman would like to see a future where the patient is entitled to receive all the information they need in order to decide how best to move forward.
“What we’ve seen up to now is the embryologist saying: ‘I will overlay what my needs are into patients and make my best guess of what’s best for them’. But that has to change and we need to get to the point where the patient is engaged and empowered, not taking a back seat,” she adds.
“That fluidity of information will give them more energy to be able to go through the entire journey, even through the disappointing aspects of it, because they’ve participated in the whole process. And this is very much the direction where Fairtility is going.”
For more information, visit fairtility.com
Insight
Fertility rate in England and Wales hits record low, new figures reveal

The fertility rate in England and Wales fell to a record low of 1.39 children per woman in 2025, down from 1.41 a year earlier.
New figures show that parts of London and cities with major universities accounted for many of the areas with the lowest local fertility rates.
The City of London recorded the lowest rate in 2025 at 0.37 children per woman, followed by Cambridge at 0.87 and the London boroughs of Islington and Westminster at 0.90.
The Office for National Statistics (ONS) defines the fertility rate as the average number of live children women would expect to have over their childbearing lives.
Brighton & Hove recorded a rate of 0.95, followed by Southwark at 0.97 and Norwich at 0.98.
Exeter, Oxford and York, along with the London boroughs of Camden and Hammersmith & Fulham, each recorded 1.01 children per woman.
At the other end of the table, Pendle in Lancashire and Luton in Bedfordshire had the highest rate at 1.93.
They were followed by Oldham in Greater Manchester at 1.87, Bradford in West Yorkshire at 1.84 and Barking & Dagenham in London at 1.83.
The overall fertility rate for England and Wales declined from 1.41 in 2024 to 1.39 in 2025.
A rate of around 2.1 is needed for a population to remain stable over time when the impact of migration is excluded.
Twelve of the 25 local authorities with the lowest fertility rates in 2025 were in London.
In Wales, Swansea recorded the lowest fertility rate at 1.18, while Carmarthenshire, the Isle of Anglesey and Newport each had the highest rate at 1.48.
There were 585,396 live births in England and Wales in 2025, down from 594,677 in 2024 and the lowest number since 1977.
Live births fell across every region in England. The West Midlands recorded the largest percentage decline at 3.1 per cent, while the North East had the smallest at 0.3 per cent.
The average age of parents also increased slightly.
Mothers had a provisional standardised mean age of 31.1 in 2025, compared with 31.0 in 2024. Fathers had an average age of 34.0, up from 33.9.
In 1975, the average age was 26.4 for mothers and 29.5 for fathers.
The proportion of births where the mother was born outside the UK also increased, from 20.8 per cent in 2005 to 27.5 per cent in 2015 and 34.6 per cent in 2025.
India was the most common country of birth for non-UK-born mothers in 2025 for the fourth consecutive year.
It was followed by Pakistan, Nigeria and Romania.
In 2025, 56.4 per cent of births were to parents who were both born in the UK, down from 62.7 per cent in 2015.
Hormonal health
Weight loss surgery improves menstrual health and PMOS symptoms, study finds

Weight loss surgery was linked to more regular periods and fewer polyendocrine metabolic ovarian syndrome (PMOS) symptoms in women aged 18 to 45 living with obesity in a recent study.
The researchers recommend that women undergoing the procedure have access to preconception care and reproductive counselling to support their reproductive health.
Researchers at the University of Surrey analysed data over 24 months from 84 women who underwent bariatric surgery and 18 women living with obesity who did not have surgery.
Of those who underwent surgery, 49 had gastric bypass procedures and 35 had gastric sleeve surgery.
Women who underwent metabolic bariatric surgery lost more than 30kg on average at 12 and 24 months after the procedure.
Among women with polycystic ovaries, the condition persisted in only 10 per cent after 24 months.
Women also reported a resolution of clinical hirsutism, or excess body hair, by 12 months.
Women who had previously experienced irregular periods reported more regular menstrual cycles after surgery.
Professor Martin Whyte, co-author of the study and professor of metabolic medicine at the University of Surrey, said: “A large proportion of those undergoing bariatric surgery are women of reproductive age, who may be planning a pregnancy in the coming years.
“So much remains unknown about the impact of this type of surgery on women who are planning to have children.
“This raises the question of when the ideal time after surgery is to conceive.”
Women have a higher prevalence of obesity than men, with 57 per cent of women in the UK classified as overweight and 27 per cent living with obesity, which can affect fertility and the health of an unborn baby.
The researchers said 17 women had healthy pregnancies following surgery.
Although this was not specifically examined in the study, no difference in birth weight was observed between babies conceived within or after the first year.
Dr Kathryn Hart, co-author of the study and associate professor in nutrition and dietetics at the University of Surrey, said: “What we have found is that bariatric surgery positively affects the reproductive health of women living with obesity and can improve the likelihood of them having a healthy pregnancy after surgery.
“Dysregulated hormone levels, irregular periods and conditions such as polycystic ovaries are affected by obesity.
“By reducing this, what we have seen is that it can lead to improvements without the need for medication.
“We would suggest that clinicians consider medical intervention for obesity to treat irregularities in the menstrual cycle and issues with fertility.”
Fertility
Scottish gov to consider IVF for single women

The Scottish government has launched a national review into whether NHS IVF access should be extended to single women.
The review will also consider whether wider access should be offered to couples who have children from previous relationships.
Health secretary Angela Constance said: “Access to NHS IVF treatment should be fair, timely and reflect the way people’s lives and families look today.”
Most single women are not currently eligible for NHS IVF treatment in Scotland.
Campaigners have welcomed the review.
Katie Rollings of Fertility Action said: “It’s an essential and long-awaited decision that will impact a huge number of people who are struggling to grow their families.
She said there is “no evidence” that having two parents rather than one determines whether a child will thrive.
She added: “What matters is whether a child is loved, safe, supported and has stable, positive relationships around them.”
Figures from the Human Fertilisation and Embryology Authority show Scotland is the only UK nation where NHS-funded IVF cycles outnumber privately funded cycles.
In 2024, more than 6,000 cycles of fertility treatment were carried out among more than 4,000 patients in Scotland. Both figures were slightly lower than the record highs recorded in 2022.
The past 20 years have also seen a rise in the number of same-sex female couples and single women receiving fertility treatment.
In 2024, 625 IVF cycles were carried out for women in same-sex couples in Scotland, with more than one third funded by the NHS.
There were 330 cycles involving single women, of which 50 were NHS-funded.
In England, single women can access IVF through the NHS, although eligibility varies according to the local health trust’s policy.
Current Scottish rules state that couples are eligible if they have been living in a stable relationship for two years and neither partner has been sterilised.
Couples where one partner already has a child can be eligible, but those where both partners have children from previous relationships are not.
Eligibility rules also require a body mass index above 18.5 and below 30, and state that couples must not smoke, drink alcohol or take drugs during treatment. The mother must be under 42.
The Scottish government said the review would also examine consistency of access to fertility preservation, including during cancer treatment, as well as reducing waiting times for donor eggs and sperm.
Same-sex female couples already have access to NHS IVF, but they can face long waits for donor eggs or sperm, as can heterosexual couples who require donor treatment.
The National Fertility Group will lead the review and make “costed, demand-modelled recommendations”, which are due to be published by early summer 2027.
The group will include fertility experts from Scotland’s four NHS-assisted conception units in Glasgow, Edinburgh, Aberdeen and Dundee.
Prof Sarah Martins Da Silva, an NHS consultant and chair of fertility medicine at Dundee University, said there were questions to be answered in a resource-stretched NHS.
“As a fertility specialist I’m never going to be disappointed if the criteria is widened,” she said.
“But with single people, as an NHS clinician looking at the competing demands we have, I’d ask the question about whether being single is a health condition that needs to be funded.”
Da Silva said NHS waiting lists were full of couples who require donated eggs or sperm because of medical conditions including cancer and could face longer waits.
“It’s slightly a disservice to them,” she said.
“There would need to be a real investment and resource without making everybody wait an extraordinary long time.
“With the current financial environment we work in, if you’re talking about new money, where would that come from?”
She said she would welcome changes that encouraged more people to donate eggs or sperm and questioned whether arguments about children needing two parents were necessarily relevant to the debate.
“On the one hand bringing up a child is quite an expensive process, and if you don’t have that support, it can be very difficult.
“But on the other hand, many people start off as a couple and divorce.”
Da Silva also welcomed plans for the review to consider eligibility for couples who already have children, describing the move as “fantastic”.
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